Which one would they use: This is just like Event 201, right? They used the coronavirus image in Event 201 and people go: “How did they guess it was going to be coronavirus?” They didn’t guess. That was their scenario. They laid it out.
Event 201 Recap: Entities that were affiliated with the WHO’s Global Preparedness Monitoring Board (GPMB) were instrumental in the Open Philanthropy-funded global coronavirus pandemic “desktop” exercise Event 201 in October 2019. This event, funded by the principal investor in Sherlock Biosciences (a beneficiary of the SARS CoV-2 EUA for CRISPR technology) and linking interlocking funding partner, the Bill and Melinda Gates Foundation into the GPMB mandated a respiratory disease global preparedness exercise to be completed by September 2020 and alerted us to anticipate an “epidemic” scenario. (Read more: ‘The Proposed Indictment’, Dr. David Martin, 2021)
Select Agents and Toxins List
The following biological agents and toxins have been determined to have the potential to pose a severe threat to both human and animal health, to plant health, or to animal and plant products. An attenuated strain of a select agent or an inactive form of a select toxin may be excluded from the requirements of the Select Agent Regulations. Here is a list of excluded agents and toxins.
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HHS and USDA Select Agents and Toxins
7 CFR Part 331, 9 CFR Part 121, and 42 CFR Part 73
HHS Select Agents and Toxins
Abrin [6]
Bacillus cereus Biovar anthracis [1]
Botulinum neurotoxins [1][6]
Botulinum neurotoxin producing species of Clostridium [1]
Conotoxins (Short, paralytic alpha conotoxins containing the following amino acid sequence X1CCX2PACGX3X4X5X6CX7) [6]
Coxiella burnetii [8]
Crimean-Congo haemorrhagic fever virus
Diacetoxyscirpenol [6]
Eastern equine encephalitis virus [4][5]
Ebolavirus [1]
Francisella tularensis [1]
Lassa fever virus
Lujo virus
Marburg virus [1]
Monkeypox virus [4]
Reconstructed replication competent forms of the 1918 pandemic influenza virus containing any portion of the coding regions of all eight gene segments (Reconstructed 1918 Influenza virus)
Ricin [6]
Rickettsia prowazekii
Severe acute respiratory syndrome coronavirus (SARS-CoV) [5]
SARS-CoV/SARS-CoV-2 chimeric viruses resulting from any deliberate manipulation of SARS-CoV-2 to incorporate nucleic acids coding for SARS-CoV virulence factors
Saxitoxin [6]
South American Haemorrhagic Fever viruses:
Chapare
Guanarito
Junín
Machupo
Sabia
Staphylococcal enterotoxins (subtypes A,B,C,D,E) [6]
T-2 toxin [6]
Tetrodotoxin [6]
Tick-borne encephalitis complex (flavi) viruses:
Far Eastern subtype [5]
Siberian subtype [5]
Kyasanur Forest disease virus [5]
Omsk hemorrhagic fever virus [5]
Variola major virus (Smallpox virus) [1]
Variola minor virus (Alastrim) [1]
Yersinia pestis [1]
Overlap Select Agents and Toxins
Bacillus anthracis [1]
Bacillus anthracis Pasteur strain
Burkholderia mallei [1]
Burkholderia pseudomallei [1]
Hendra virus
Nipah virus [1]
Rift Valley fever virus
Venezuelan equine encephalitis virus [4][5]
USDA Veterinary Services (VS)
Select Agents and Toxins
African swine fever virus
Avian influenza virus [4]
Classical swine fever virus [5]
Foot-and-mouth disease virus [1][5]
Goat pox virus
Lumpy skin disease virus
Mycoplasma capricolum [4]
Mycoplasma mycoides [4]
Newcastle disease virus [3][4]
Peste des petits ruminants virus
Rinderpest virus [1]
Sheep pox virus
Swine vesicular disease virus [5]
USDA Plant Protection And Quarantine (PPQ)
Select Agents and Toxins
Coniothyrium glycines
(formerly Phoma glycinicola and Pyrenochaeta glycines)
Ralstonia solanacearum [7]
Rathayibacter toxicus
Sclerophthora rayssiae [7]
Synchytrium endobioticum
Xanthomonas oryzae
[1] Denotes Tier 1 Agent
[2] C = Cysteine residues are all present as disulfides, with the 1st and 3rd Cysteine, and the 2nd and 4th Cysteine forming specific disulfide bridges; The consensus sequence includes known toxins a-MI and a-GI (shown above) as well as a-GIA, Ac1.1a, a-CnIA, a-CnIB; X1 = any amino acid(s) or Des-X; X2 = Asparagine or Histidine; P = Proline; A = Alanine; G = Glycine; X3 = Arginine or Lysine; X4 = Asparagine, Histidine, Lysine, Arginine, Tyrosine, Phenylalanine or Tryptophan; X5 = Tyrosine, Phenylalanine, or Tryptophan; X6 = Serine, Threonine, Glutamate, Aspartate, Glutamine, or Asparagine; X7 = Any amino acid(s) or Des X and; “Des X” = “an amino acid does not have to be present at this position.” For example if a peptide sequence were XCCHPA then the related peptide CCHPA would be designated as Des-X.
[3] A virulent Newcastle disease virus (avian paramyxovirus serotype 1) has an intracerebral pathogenicity index in day-old chicks (Gallus gallus) of 0.7 or greater or has an amino acid sequence at the fusion (F) protein cleavage site that is consistent with virulent strains of Newcastle disease virus. A failure to detect a cleavage site that is consistent with virulent strains does not confirm the absence of a virulent virus.
[4] Select agents that meet any of the following criteria are excluded from the requirements of this part: Any low pathogenic strains of avian influenza virus, Madariaga virus, Clade II Monkeypox, any strain of Newcastle disease virus which does not meet the criteria for virulent Newcastle disease virus, all subspecies Mycoplasma capricolum except subspecies capripneumoniae (contagious caprine pleuropneumonia), all subspecies Mycoplasma mycoides except subspecies mycoides small colony (Mmm SC) (contagious bovine pleuropneumonia), and any subtypes of Venezuelan equine encephalitis virus except for Subtypes IAB or IC, provided that the individual or entity can verify that the agent is within the exclusion category.
[5] For determining the regulatory status of nucleic acids that are capable of producing infectious forms of select agent viruses, please reference guidance here.
[6] For determining the regulatory status of Recombinant and/or Synthetic nucleic acids that encode for the toxic form(s) of any select toxins if the nucleic acids (i) can be expressed in vivo or in vitro, or (ii) are in a vector or recombinant host genome and can be expressed in vivo or in vitro; please reference guidance here.
[7] Select agents or toxins that meet any of the following criteria are excluded from the requirements of this part: Any subspecies of Ralstonia solanacearum except race 3, biovar 2 and all subspecies of Sclerophthora rayssiae except var. zeae, provided that the individual or entity can identify that the agent is within the exclusion category.
[8] Coxiella burnetii Phase II, Nine Mile Strain, plaque purified clone 4 with reversion to wildtype cbu0533 is a select agent.
Last Reviewed: January 14, 2025
Source: Division of Regulatory Science and Compliance. CDC